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A multimodal lifestyle intervention complemented with epigallocatechin gallate to prevent cognitive decline in APOE- ɛ4 carriers with Subjective Cognitive Decline: a randomized, double-blinded clinical trial (PENSA study)

dc.contributor.authorForcano Gamazo, Laura
dc.contributor.authorSoldevila-Domenech, Natalia
dc.contributor.authorBoronat, Anna
dc.contributor.authorSánchez-Benavides, Gonzalo Andrés
dc.contributor.authorPuig-Pijoan, Albert
dc.contributor.authorLorenzo, Thais
dc.contributor.authorAldea-Perona, Ana
dc.contributor.authorSuárez-Calvet, Marc
dc.contributor.authorCuenca Royo, Aida
dc.contributor.authorGispert, Juan Domingo
dc.contributor.authorGomis-Gonzalez, Maria
dc.contributor.authorMinguillon, Carolina
dc.contributor.authorDiaz-Pellicer, Patricia
dc.contributor.authorFauria, Karine
dc.contributor.authorPiera, Iris
dc.contributor.authorLangohr, Klaus
dc.contributor.authorDierssen, Mara
dc.contributor.authorPizarro Lozano, Nieves
dc.contributor.authorMur, Esther
dc.contributor.authorGrau-Rivera, Oriol
dc.contributor.authorde la Torre, Rafael
dc.date.accessioned2026-06-01T12:20:35Z
dc.date.available2026-06-01T12:20:35Z
dc.date.issued2025-09
dc.identifier.citationForcano Gamazo L, Soldevila-Domenech N, Boronat A, Sánchez-Benavides GA, Puig-Pijoan A, Lorenzo T, et al. A multimodal lifestyle intervention complemented with epigallocatechin gallate to prevent cognitive decline in APOE- ɛ4 carriers with Subjective Cognitive Decline: a randomized, double-blinded clinical trial (PENSA study). J Prev Alzheimers Dis. 2025 Sep;12(8):100271. DOI: 10.1016/j.tjpad.2025.100271ca
dc.identifier.issn2426-0266ca
dc.identifier.urihttps://hdl.handle.net/20.500.12367/3232
dc.description.abstractBackground: The potential of dietary compounds to enhance the effects of multimodal lifestyle interventions (MLIs) on cognition in individuals at high risk of cognitive impairment remains unclear. Objectives: To assess whether the addition of a green tea extract enriched with epigallocatechin-3-gallate (EGCG) enhances the effects of an MLI. Design: Double-blind, randomized, two-arm, and placebo-controlled trial. Exploratory comparisons were made with a non-randomized group (NRG) receiving healthy lifestyle recommendations. Setting: Population-based study conducted in Barcelona, Spain. [...]ca
dc.format.extent12 p.ca
dc.language.isoengca
dc.publisherSpringer Natureca
dc.relation.ispartofThe Journal of Prevention of Alzheimer's Disease. 2025 Sep;12(8):100271ca
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.otherMultimodal lifestyle interventionca
dc.subject.otherPreventionca
dc.subject.otherAPOE-ɛ4ca
dc.subject.otherEpigallocatechin-3-gallateca
dc.subject.otherSubjective Cognitive Declineca
dc.subject.otherRandomized Controlled Trialca
dc.titleA multimodal lifestyle intervention complemented with epigallocatechin gallate to prevent cognitive decline in APOE- ɛ4 carriers with Subjective Cognitive Decline: a randomized, double-blinded clinical trial (PENSA study)ca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.identifier.doi10.1016/j.tjpad.2025.100271ca


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Attribution 4.0 International
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