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dc.contributor.advisor
dc.contributor.authorLópez-de-Ipiña, Karmele
dc.contributor.authorSolé-Casals, Jordi
dc.contributor.authorSánchez-Méndez, José Ignacio
dc.contributor.authorRomero-Garcia, Rafael
dc.contributor.authorFernandez, Elsa
dc.contributor.authorRequejo, C.
dc.contributor.authorPoologaindran, Anujan
dc.contributor.authorFaundez-Zanuy, Marcos
dc.contributor.authorMarti Masso, Jose Felix
dc.contributor.authorBergareche, Alberto
dc.contributor.authorSuckling, John
dc.contributor.otherTecnoCampus. Escola Superior Politècnica (ESUPT)ca
dc.date.accessioned2022-09-23T09:37:01Z
dc.date.available2022-09-23T09:37:01Z
dc.date.issued2021-06-08
dc.identifier.citationLópez-de-Ipiña K, Solé-Casals J, Sánchez-Méndez JI, Romero-Garcia R, Fernandez E, Requejo C, et al. Analysis of fine motor skills in essential tremor: combining neuroimaging and handwriting biomarkers for early management. Front Hum Neurosci. 2021 Jun 8;15:648573. DOI: 10.3389/fnhum.2021.648573
dc.identifier.issn1662-5161
dc.identifier.urihttp://hdl.handle.net/20.500.12367/1915
dc.description.abstractEssential tremor (ET) is a highly prevalent neurological disorder characterized by actioninduced tremors involving the hand, voice, head, and/or face. Importantly, hand tremor is present in nearly all forms of ET, resulting in impaired fine motor skills and diminished quality of life. To advance early diagnostic approaches for ET, automated handwriting tasks and magnetic resonance imaging (MRI) offer an opportunity to develop early essential clinical biomarkers. In this study, we present a novel approach for the early clinical diagnosis and monitoring of ET based on integrating handwriting and neuroimaging analysis. We demonstrate how the analysis of fine motor skills, as measured by an automated Archimedes’ spiral task, is correlated with neuroimaging biomarkers for ET. Together, we present a novel modeling approach that can serve as a complementary and promising support tool for the clinical diagnosis of ET and a large range of tremors.ca
dc.format.extent11 p.ca
dc.language.isoengca
dc.publisherFrontiers Media SAca
dc.relation.ispartofFrontiers in Human Neuroscience. 2021 Jun 8;15:648573
dc.rightsCopyright © 2021 Lopez-de-Ipina, Solé-Casals, Sánchez-Méndez, Romero-Garcia, Fernandez, Requejo, Poologaindran, Faúndez-Zanuy, Martí-Massó, Bergareche and Suckling. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.otherEssential tremorca
dc.subject.otherFine motor skills
dc.subject.otherNeuroimaging
dc.subject.otherHandwriting
dc.subject.otherEarly management
dc.titleAnalysis of fine motor skills in essential tremor: combining neuroimaging and handwriting biomarkers for early managementca
dc.typeinfo:eu-repo/semantics/articleca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.identifier.doidoi.org/10.3389/fnhum.2021.648573ca


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Copyright © 2021 Lopez-de-Ipina, Solé-Casals, Sánchez-Méndez, Romero-Garcia, Fernandez, Requejo, Poologaindran, Faúndez-Zanuy, Martí-Massó, Bergareche and Suckling. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/
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